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Kidneyresearchcenter Cologne

Forschung in Labor und Klinik

Wissenschaft & Forschnung

Nephrolab Cologne

Grundlagenforschung zu Nierenerkrankungen

Forschungsverbund

Sybacol - System Biology of Ageing Cologne

Initiative zur Alternsforschung

Klinische Forschergruppe

KFO 329 - Podozyten und FSGS

Krankheitswege und Behandlungsmöglichkeiten

Förder:innen und Interessent:innen

REN - Research Excellence in Nephrology

Verein zur Förderung der Nephrologie

Patient:innen und Angehörige

AD(H)PKD

Diagnose, Forschung und Therapie

REACT - 2020

Diagnose, Forschung und Therapie

Research Projects

Epigenetic determinants of genome stability for mammalian tissue

Project - 1

Epigenetic determinants of genome stability for mammalian tissue

Robert Hänsel-Hertsch

Mechanical-stress induced DNA damage and genome mechanoprotection in cellular and organismal homeostasis

Project - 2

Mechanical-stress induced DNA damage and genome mechanoprotection in cellular and organismal homeostasis

Björn Schumacher, Sara Wickström

Epigenetic regulation of the cellular homeostasis amid transcription-blocking DNA damage during development and aging

Project - 3

Epigenetic regulation of the cellular homeostasis amid transcription-blocking DNA damage during development and aging

Björn Schumacher, Siyao Wang

Coordination of DNA damage response and aging by ubiquitin signaling

Project - 4

Coordination of DNA damage response and aging by ubiquitin signaling

Thorsten Hoppe

Ubiquilins in DNA repair and neurodegeneration

Project - 5

Ubiquilins in DNA repair and neurodegeneration

Ron Jachimowicz

Mechanism and consequences of SLX4IP- and ERCC1-XPF-dependent telomere dysfunction

Project - 6

Mechanism and consequences of SLX4IP- and ERCC1-XPF-dependent telomere dysfunction

Stephanie Panier

The impact of chronic genome instability on tissue homeostasis and how reduced diet alleviates DNA damage-driven functional deterioration

Project - 7

The impact of chronic genome instability on tissue homeostasis and how reduced diet alleviates DNA damage-driven functional deterioration

Jan Hoeijmakers

Metabolic deregulation, genome instability, and the progression of chronic kidney disease

Project - 8

Metabolic deregulation, genome instability, and the progression of chronic kidney disease

Thomas Benzing, Bernhard Schermer

Central Projects

A computational platform for data support, integration and management

Z - 1

A computational platform for data support, integration and management

David H. Meyer

Central Coordination Project

Z - 2

Central Coordination Project

Simon Uszkoreit